You can help prevention of the rejection by taking your drugs as advised by your doctors, presenting for follow-up visit at regular interval and following your dietary instructions. Moreover, you should immediately contact your doctor in case of decrease in output of urine, pain at the location of the transplant kidney, fever and so on. The risk of rejection (of kidney) applies even if you have the care regularly after the transplant surgery. This risk can emerge in early postoperative period or even many years after the transplant surgery. In this case, you may need to re-start on dialysis therapy. Moreover, a new kidney transplant surgery may also be performed, if your medical condition allows.